A Case Study of a 73 -Year-Old Male with Mantle Cell Lymphoma
DOI:
https://doi.org/10.26463/rjns.13_2_1Keywords:
Mantle cell lymphoma, Chemotherapy Non-Hodgkin lymphomas, Rare cancer, Elderly patientAbstract
Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin lymphomas (NHLs) characterized by a (11,14) translocation resulting in overexpression of the cyclin D1 (CCND1) gene. The MCL typically presents with advanced extra nodal, bone marrow, peripheral blood, splenic, and/or gastrointestinal involvement. Excisional biopsy of lymph node and immunohistochemistry plays an important role in the diagnosis. Standard first-line treatment consists of chemoimmunotherapy. This may result in prolonged remission, but relapse is to be expected. This is the case of a 72-year-old man with mantle cell lymphoma, admitted to hospital in December 2022 with the chief complaints of a lump in the axilla, significant weight loss, and fatigue for one month. Patient also had a previous history of osteoarthritis. He was treated with five cycles of chemotherapy with an interval of 28 days between the cycles. He was advised to consume high protein diet and to perform quadriceps and hamstring strengthening exercises. He was informed to periodically review in outpatient department and to consult a doctor if any unusual symptoms present.
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