Factors Influencing the Natural Menopause Age among Women Attending Gynaecology Outpatient Clinic at a Tertiary Care Hospital in Central India
DOI:
https://doi.org/10.26463/rjns.14_2_9Keywords:
Menarche, Menopause, Menstrual, Parity, ReproductiveAbstract
Background: A woman enters the fertility period and then eventually comes a phase when her ovaries start to malfunction. It is challenging to pinpoint the exact age at which menopause begins for each woman.
Objectives: The present study was conducted to assess the socio demographic factors, life style factors, menstrual and reproductive factors among postmenopausal women and to determine the association of these factors with the menopausal age.
Methods: The present hospital based cross-sectional study was conducted including 330 women aged 45-65 years visiting the Obstetrics and Gynaecology Outpatient Department (OPD) at a teaching hospital. The interview proforma comprised questions regarding socio-demographic profile, lifestyle factors, menstrual and reproductive factors. Statistical tests like Chi-square test and logistic regression analysis were applied. Frequency, percentage, Odds ratio (OR) with their respective 95% confidence interval was calculated and P value <0.05 was considered as statistically significant.
Results: In present study, 63.03% of women attained menopause before the age of 45 years. The odds of developing early menopause (≤45 years) among urban women were higher compared to rural women [OR: 3.39; 95% CI: 2.12-5.43]. Among married women, odds of developing early menopause (≤45 years) were 4.19 times higher as compared to unmarried, widowed, divorcee and separated females. The odds of developing early menopause among women who attained menarche at the age of ≤13 years were 52% lower than those who attained menarche at >13 years of age. The odds of developing early menopause (≤45 years) among women with parity ≤ 3 were 3.14 times (95% CI: 1.68-5.85) higher as compared to women having parity >5.
Conclusion: In this study, area of residence, marital status, socio-economic class, body mass index (BMI), history of addiction, age at menarche, age at first delivery and parity were associated with natural menopause age, indicating that social, lifestyle, and reproductive factors may have an impact on menopausal age.
References
1. World Health Organization. Menopause. Geneva: WHO; 2022. [Cited 2023 Jan 20]. Available from: [https://www.who.int/news-room/fact sheets/detail/ menopause#:~:text=This%20means%20that%20the%20ovaries,55%20years%20for%20 women%20worldwide.
2. Peacock K, Ketvertis KM. Menopause. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [Cited on 25 March 2023] Available from: https://www.ncbi.nlm.nih. gov/books/NBK507826/]
3. Hyvärinen M, Karvanen J, Aukee P, et al. Predicting the age at natural menopause in middle-aged women. Menopause 2021;28(7):792-99
4. Pallikadavath S, Ogollah R, Singh A, et al. Natural menopause among women below 50 years in India: A population-based study. Indian J Med Res 2016;144(3):366-377.
5. Vinker S, Yogev Y, Kitai E, et al. Awareness of personal healthcare and menopause in menopausal women in Israel. Isr Med Assoc J 2003;5(1):31-4.
6. Lee MS, Kim JH, Park MS, et al. Factors influencing the severity of menopause symptoms in Korean post-menopausal women. J Korean Med Sci 2010;25(5):758-65.
7. Rahman SA, Zainudin SR, Mun VL. Assessment of menopausal symptoms using modified Menopause Rating Scale (MRS) among middle age women in Kuching, Sarawak, Malaysia. Asia Pac Fam Med 2010;9:1-6.
8. Dutta R, Dcruze L, Anuradha R, et al. A population based study on the menopausal symptoms in a rural area of Tamil Nadu, India. J Clin Diagn Res 2012;6(4):597-601.
9. Geeta R, Parida L. Prevalence of menopausal problems and the strategies adopted by women. Maharashtra (India). IJSR 2015;4:1-6.
10. Khan S, Shukla MK, Priya N, et al. Health seeking behavior among postmenopausal women: a knowledge, attitude and practices study. Int J Community Med Public Health 2016;3:1777-82.
11. Chuni N, Sreeramareddy CT. Frequency of symptoms, determinants of severe symptoms, validity of and cut off score for Menopause Rating Scale (MRS) as a screening tool: A cross-sectional survey among midlife Nepalese women. BMC Womens Health 2011;11(1):30.
12. Hardy R, Kuh D. Social and environmental conditions across the life course and age at menopause in a British birth cohort study. BJOG 2005;112:346-54.
13. Kapur P, Sinha B, Pereira BM. Measuring climacteric symptoms and age at natural menopause in an Indian population using the Greene Climacteric Scale. Menopause 2009;16(2):378-84.
14. Amrita S, Pradeep P, Kakoli G, et al. A study on health profile of postmenopausal women in Jamnagar district, Gujarat. Journal of Research in Medical and Dental Science 2014;2(2):25
15. Maru L, Verma R, Verma M, et al. Correlation of body mass index and age of menopause in women attending medicine and gynaecology department of a tertiary care centre. Int J Res Med Sci 2016;4:2206-9.