Seroprevalence of Human Brucellosis among Patients admitted with PUO (Pyrexia of Unknown Origin) at a Tertiary Care Hospital in North India
DOI:
https://doi.org/10.26463/rjns.14_2_8Keywords:
Human Brucellosis, Seroprevalence, PUO, Raw milkAbstract
Background: Brucellosis is a disease reported in many parts of the world including India and the disease is also one of the important causes of PUO (Pyrexia of Unknown Origin). The present study was conducted with an aim to determine the seroprevalence of human Brucellosis in patients reporting with PUO.
Method: A cross-sectional hospital-based study was conducted at a tertiary care medical teaching institute in Northern India. A total of 369 serum samples were collected from PUO cases and tested for human Brucellosis by using Rose Bengal Plate Agglutination Test (RBPT), Serum Tube Agglutination Test (STAT), Enzyme linked Immunoassay (ELISA).
Results: Overall seroprevalence in our study was found to be 2.98% (0.5%, 0.8%, and 1.6% by RBPT, STAT and ELISA, respectively).
Conclusion: In spite of the low prevalence of human Brucellosis, clinicians must maintain a high index of suspicion for the possibility of a patient suffering from Brucellosis while encountering a case of PUO and it is advisable to elicit history in terms of certain occupations and risk factors for Brucellosis in patients reporting with PUO.
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